By Topic

Pinched flow fractionation (PFF) for continuous particle separation in a microfluidic device

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
M. Nakashima ; Dept. of Chem. & Biotechnol., Tokyo Univ., Japan ; M. Yamada ; M. Seki

We propose here a new method for the continuous and accurate sizing of particles using fluid focusing and spreading in a microdevice, named 'pinched flow fractionation (PFF)'. Particles suspended in liquid were continuously introduced into a microchannel having a specific geometry, and were aligned to one sidewall by the other liquid flow without particles, and then separated according to their sizes by the spreading flow profile inside the channel. For the application of this method, we have successfully performed separation of the mixture of micro polystyrene beads. This method is highly advantageous because of its accuracy, applicability and simplicity in operation.

Published in:

Micro Electro Mechanical Systems, 2004. 17th IEEE International Conference on. (MEMS)

Date of Conference: