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We address the interaction between TCP and RLC (Radio Link Control), the link layer retransmission protocol in W-CDMA, a 3rd generation cellular wireless network technology, in evaluating TCP performance in following points; l) Supress delay-jitter in link layer to avoid excess retransmissions. 2) Clarify the trade-off between jitter-suppression and link utilization to improve TCP throughput. 3) Optimize the link layer and TCP parameters. We show how to find the TCP and link ARQ parameters that yield optimum overall performance; simulations and emulation confirm their effectiveness. The coexistence of ARQ and TCP can lead to inefficient interaction; the delay-jitter on the link layer may trigger spurious TCP retransmission. The solution is to suppress jitter on the link layer. To manage the trade-off between this suppression and link utilization, we optimized with link parameter.