By Topic

Detection of biological molecules: from self-assembled films to self-integrated devices

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

1 Author(s)
Levicky, R. ; Dept. of Chem. Eng., Columbia Univ., New York, NY, USA

Detection of molecules involved with the functioning of living things impacts a broad spectrum of applications from pathogen detection to drug development and biochemically-guided medical care. Biological molecules are often detected from an analyte mixture by selective binding to a solid support. The function of the sensor is then to detect such surface binding events, to convert them (typically) to an electrical signal, and to extract information from the signal such as identity and concentration of the analyte. These functions, simple in principle, pose a number of challenges in practice. Under optimal conditions only the analyte of interest should interact with the sensor. We provide an overview of methods used to derivatize surfaces with biomolecular probes on silica-like and metal supports.

Published in:

Computer Design, 2003. Proceedings. 21st International Conference on

Date of Conference:

13-15 Oct. 2003