Cart (Loading....) | Create Account
Close category search window
 

Stem cell harvesting device with passive flexible drilling unit for bone marrow transplantation

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

7 Author(s)
Ohashi, K. ; Graduate Sch. of Inf. Sci. & Technol., Univ. of Tokyo, Japan ; Hata, N. ; Matsumura, T. ; Ogata, T.
more authors

A novel device is described for efficiently harvesting bone marrow in bone marrow transplantation that uses a newly developed passive flexible drilling unit and suction mechanism. The device reduces the invasiveness of bone marrow harvesting by collecting stem cells from the iliac bone with minimal punctures and by reducing the operation time and the contamination by T-cells. The device is inserted into the medullary space from the iliac crest and aspirates the bone marrow while an end mill on the tip of the drilling unit drills through the cancellous bone to create a curved path. In vitro and in vivo pig studies showed that the device can be inserted into the medullary space of the pig iliac bone, 131 × 32.1 mm/min, and used to harvest about six times as much bone marrow per puncture as the conventional aspiration method. They also showed that the device can generate higher and longer negative pressure (-76.9 kPa for 5.96 s) than the aspiration method (-41.8 kPa for 4.97 s). The device, when applied in clinical study, will reduce invasiveness by harvesting denser graft from a wider area of the iliac bone compared to the conventional aspiration method, although minimal puncturing is required.

Published in:

Robotics and Automation, IEEE Transactions on  (Volume:19 ,  Issue: 5 )

Date of Publication:

Oct. 2003

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.