By Topic

Modeling electric field transfer of excitation at cell junctions

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

2 Author(s)
Sperelakis, Nicholas ; Dept. of Molecular & Cellular Physiol., Univ. of Cincinnati Coll. of Medicine, OH, USA ; Ramasamy, L.

The electric field (EF) model was first developed on a "breadboard" using physical electric components (e.g., resistors, capacitors, batteries) and was then modeled mathematically by a series of differential equations and matrix equations and simulated on a large computer (CDC-6400). The results obtained by the two methods agreed very closely. However, these two methods of analysis are quite cumbersome. Therefore, in order to simplify the EF simulation, we wanted to model it on the PSpice program. In this article we discuss how we succeeded in demonstrating transmission of excitation from cell to cell in cardiac muscle and smooth muscle based on EF transmission at the cell junctions.

Published in:

Engineering in Medicine and Biology Magazine, IEEE  (Volume:21 ,  Issue: 6 )