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Modeling biochemical networks and excitation-contraction coupling

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3 Author(s)
Saucerman, J.J. ; Dept. of Bioeng., Univ. of California, San Diego, CA, USA ; Michailova, A.P. ; McCulloch, A.D.

Integrative computational models are being developed to couple biochemical networks with the physiological functions that they regulate. Models of interacting cell sub-systems including signal transduction, electrophysiology and metabolism are presented. These models allow us to explore hypotheses regarding physiological and pathophysiological function in the cardiac myocyte.

Published in:
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint  (Volume:3 )

Date of Conference: 23-26 Oct. 2002

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