Integrative computational models are being developed to couple biochemical networks with the physiological functions that they regulate. Models of interacting cell sub-systems including signal transduction, electrophysiology and metabolism are presented. These models allow us to explore hypotheses regarding physiological and pathophysiological function in the cardiac myocyte.
Published in:
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
(Volume:3
)
Date of Conference: 23-26 Oct. 2002