A theoretical method is presented which uses wave-guiding principles to construct a focused point of stimulation at any location within a region of electrically-excitable tissue. The excitation is formed through the constructive interference of different frequency wave energies, traveling at frequency-dependent velocities, which coalesce at the stimulation point. Further energy is brought to the stimulation point through reflection(s) at the boundaries of the wave-guiding structure. The resulting excitation signal depends upon several factors, including pulse envelope and duration, allowable frequency range, and stimulation time. A necessary trade-off exists amongst stimulation time, pulse duration, and the degree of focus.
Published in:
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
(Volume:3
)
Date of Conference: 23-26 Oct. 2002