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Cell Adhesions on Nanoturf Surfaces

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5 Author(s)
Chang-Hwan Choi ; Mechanical & Aerospace Engineering Dept., University of California at Los Angeles (UCLA), USA ; Hagvall, S.H. ; Dunn, J.C.Y. ; Wu, B.M.
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We report on various aspects of cell adhesion of fibrolasts over densely-populated sharp-tip nano-post structures, which we term “ NanoTurf”. The ability to control the size, shape, and aspect ratio of the nanostructures enabled the study on the effect of surface three-dimensionality of the cell-matrix adhesion in detail. To our best knowledge, this is the first systematic investigation of the nanometric three-dimensional surface topography effect on cell adhesions.

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Micro Electro Mechanical Systems, 2006. MEMS 2006 Istanbul. 19th IEEE International Conference on

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