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Generation of large-area tunable uniform electric fields in microfluidic arrays for rapid DNA separation

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6 Author(s)
Huang, L.R. ; Dept. of Electr. Eng., Princeton Univ., NJ, USA ; Tegenfeldt, J.O. ; Kraeft, J.J. ; Sturm, J.C.
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Control of electric fields over large areas is crucial for the accurate delivery and manipulation of biologically important molecules in microfluidic systems. In this paper we present a novel method for generating tunable uniform electric fields over large microfluidic arrays in two dimensions, and its application to a microfabricated device that separates genomic DNA. The device fractionates large DNA molecules over three orders of magnitude faster than conventional methods.

Published in:

Electron Devices Meeting, 2001. IEDM '01. Technical Digest. International

Date of Conference:

2-5 Dec. 2001