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Rigid registration of 3-D ultrasound with MR images: a new approach combining intensity and gradient information

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4 Author(s)
Roche, A. ; Inst. Nat. de Recherche en Inf. et Autom., Sophia Antipolis, France ; Pennec, X. ; Malandain, G. ; Ayache, N.

Presents a new image-based technique to rigidly register intraoperative three-dimensional ultrasound (US) with preoperative magnetic resonance (MR) images. Automatic registration is achieved by maximization of a similarity measure which generalizes the correlation ratio, and whose novelty is to incorporate multivariate information from the MR data (intensity and gradient). In addition, the similarity measure is built upon a robust intensity-based distance measure, which makes it possible to handle a variety of US artifacts. A cross-validation study has been carried out using a number of phantom and clinical data. This indicates that the method is quite robust and that the worst registration errors are of the order of the MR image resolution.

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Medical Imaging, IEEE Transactions on  (Volume:20 ,  Issue: 10 )