By Topic

Validation of a Na+-Ca++ regulation model for high variations of the inner cell conditions

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Gonzalez-Velez, V. ; Dept. of Basic. Sci., UAM, Azcapotzalco, Mexico ; Godinez-Fernandez, J.R. ; Aguilar-Pliego, J. ; Morales-Guzman, J.D.

The Na+-Ca++ exchanger is a reversible regulation mechanism which can work to deplete or augment the internal Ca++ concentration, as long as there is enough free Na+ . A Ca++ regulation simulator has been demonstrated to be reliable for simulating the cell response to ionic and electrical stimuli, providing the internal Ca++ concentration is in the physiological range at the beginning of the simulation. In this paper, we pose several corrections to the original model and we also discuss the inclusion of additional kinetic and sensitivity parameters of the mechanisms in order to follow the biological role of the exchanging current

Published in:

Computer-Based Medical Systems, 2001. CBMS 2001. Proceedings. 14th IEEE Symposium on

Date of Conference: