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Closed- versus open-loop assessment of heart rate baroreflex

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3 Author(s)
R. Barbieri ; Children's Heart Center, Med. Univ. of South Carolina, SC, USA ; G. Parati ; J. P. Saul

The autoregressive multivariate techniques described are based on simplified models of the entire cardiovascular system and satisfy both the requirements of not perturbing the system and providing a closed-loop evaluation of the interactions between R-R interval and arterial blood pressure. The closed-loop analysis is also able to calculate some of the indices previously used for baroreflex quantification, allowing for a direct comparison of the different approaches

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IEEE Engineering in Medicine and Biology Magazine  (Volume:20 ,  Issue: 2 )