By Topic

Excited-state intramolecular proton transfer in 4'-amino derivatives of 3-hydroxyflavone in organic solvents and biomembranes

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Kruchenok, J.V. ; Stepanov Inst. of Phys, Acad. of Sci., Minsk, Byelorussia ; Nemkovich, N.A. ; Sobchuk, A.N. ; Petrov, E.P.
more authors

Summary form only given. It is well known that 3-hydroxyflavone exhibits the solvent-controlled excited-state intramolecular proton transfer (ESIPT) reaction and therefore its derivatives can serve as sensitive fluorescent probes for investigating microparameters of biological membranes and macromolecules. We present results of steady-state and time-resolved fluorescence spectroscopy investigations of 4'-diethylamino (FET) and 4'-(15-azacrown-5) (FCR) derivatives of 3-hydroxyflavone in simple and binary aprotic solvents, and human erythrocyte membranes. The presence of the 4'-amino substituent in the 3-hydroxyflavone molecule leads to an increase in its dipole moment, which results in more pronounced solute-solvent effects. Due to the different sizes of substituents in the FET and FCR molecules it is expected that these compounds can be used as fluorescent probes sensing different regions of a biological membrane.

Published in:

Quantum Electronics Conference, 2000. Conference Digest. 2000 International

Date of Conference:

10-15 Sept. 2000