Highly parallel integrated microfluidic biochannel arrays

Microfluidic biochannel arrays that integrates massively parallel microfluidic channels with Motorola glass-based microarray biochips have been successfully developed. We demonstrated that such a device allows DNA hybridization assays to be performed in a miniaturized and highly parallel fashion. The biochannel arrays are a new DNA diagnostics platform that has several desirable features such as single-use and cost-effective, highly parallel (up to 52 protocols in parallel), and processed rapidly. Additionally, only nanoliter-volumes (/spl sim/100 nL) of DNA sample/reagents are consumed per array.