Cart (Loading....) | Create Account
Close category search window
 

ACAPELLA-1K: a biomechatronic fluid handling system for genome analysis that processes 1000 samples in 8 hours

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Meldrum, D.R. ; Dept. of Electr. Eng., Washington Univ., Seattle, WA, USA ; Evensen, H.T. ; Pence, W.H. ; Moody, S.E.
more authors

An automated biomechatronic submicroliter fluid handling system for processing deoxyribonucleic acid (DNA) has been developed in the Genomation Laboratory, Department of Electrical Engineering, University of Washington, Seattle. This first generation system, ACAPELLA-1K, can process 1000 samples in 8 h in preparation for DNA sequencing using sample volumes ten times smaller than current state-of-the art manual and automated instrumentation. The system is based upon a proof-of-concept system that was developed by the Genomation Laboratory. The ACAPELLA-1K is the first integration of modules for fluid aspiration, dispensing, mixing, transport, and thermal processing that have been designed and developed with corporate partners Orca Photonic Systems, Inc., Redmond, WA, and Engineering Arts, Mercer Island, WA. These modules, comprising piezoceramic actuators, pneumatic pumps, linear mechanisms, thermal controllers, optical sensors, electronics, computer control, and software, are described in detail. Processing statistics are presented and successful experimental results are presented

Published in:

Mechatronics, IEEE/ASME Transactions on  (Volume:5 ,  Issue: 2 )

Date of Publication:

Jun 2000

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.