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Perspectives of high power pulse generators for the boron neutron capture therapy (BNCT) of tumors

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2 Author(s)
Bluhm, H. ; Inst. fur Hochleistungsimpuls- & Mikrowellentechnik, Forschungszentrum Karlsruhe, Germany ; Hoppe, P.

In this paper, the authors discuss an epithermal neutron source suitable for the boron neutron capture therapy (BNCT) of tumors based on the /sup 7/Li(p,n)/sup 7/Be reaction. To realize this neutron source, a 5 TW pulse generator, a high power proton diode, and an appropriate target arrangement, all capable to produce up to 500 pulses in a burst mode are required. Unless a very accurate control of the proton energy can be achieved, operation close to the reaction threshold, although leading to a higher useful neutron flux, is not practicable. It is therefore proposed to use a 2.5 MeV proton beam. A new target needs to be injected after every pulse. With a repetition rate of 1 pulse per second, a treatment time of less than 10 minutes can be achieved.

Published in:

Pulsed Power Conference, 1999. Digest of Technical Papers. 12th IEEE International  (Volume:1 )

Date of Conference:

27-30 June 1999