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Spectrophotometric analysis of cortical bone

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2 Author(s)
Rai, D.V. ; Dept. of Biophys., Panjab Univ., Chandigarh, India ; Ranu, H.S.

An attempt was made to study the structural behavior of a crystal in bone composite material of rats and rabbits. A Fourier transform infrared (FTIR) spectrophotometer and computer were used to monitor the infrared spectra of five bone samples each from the rats and rabbits. The spectra indicate the absorption band in the region of 500 to 700 cm/sup -1/, with a wider bandwidth in the samples of rats as compared to rabbits. The spectra indicate that (1) the amorphous crystalline behavior of bone crystal is animal specific: (2) bone surface resorption is greater in amorphous bone; (3) cortical thickness may be affected by the bone's molecular structure; and (4) the mineral deposits on the collagen matrix are mediated through a biophysical mechanism that follows a crystallographical arrangement in the protein lattice.<>

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Engineering in Medicine and Biology Magazine, IEEE  (Volume:10 ,  Issue: 2 )