The development and analysis of biophysically and anatomically detailed computational models of physiological systems is beginning to provide an important tool for relating changes in gene expression to changes in biological function at the levels of cell and tissue in both health and disease. The authors illustrate this approach using computational models of the failing heart developed recently within their laboratory
Published in:
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
(Volume:2
)
Date of Conference: Oct 1999