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Image-guided thermal ablation with radiofrequency: new approaches and clinical experience

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1 Author(s)
Nahum Goldberg, S. ; Lab. of Minimally-Invasive Therapy, Beth Israel Deaconess Med. Centre, Boston, MA, USA

Radiofrequency (RF) tumor ablation is a reliable method for creating thermally induced coagulation necrosis using either percutaneous, image-guidance or direct surgical application of thin electrodes into treated tissues. The technical considerations for RF procedures are reviewed and considerations necessary for optimizing RF ablation are discussed. Strategies to increase the extent of induced coagulation necrosis including: multiprobe and bipolar arrays, saline infusion, and internally-cooled RF electrodes; with or without pulsed-RF or cluster technique are presented. The development and laboratory results for many of these techniques and potential biophysical limitations to RF induced coagulation, such as perfusion mediated tissue cooling (vascular flow) are likewise discussed. Additionally, initial clinical results for liver, bone and other tumors are discussed

Published in:

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint  (Volume:2 )

Date of Conference:

Oct 1999