Referenced Items are not available for this document.
Studying the effects of shear stress on the expression of tissue factor (TF) gene in cultured endothelial cells (ECs), the authors found that a GC-rich region of the promoter that contains EGR-1 and Sp1 sites is responsible for the shear stress induction of TF gene. The increased transcriptional activity is mediated through a novel mechanism of Sp1 phosphorylation, rather than DNA binding
Published in:
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
(Volume:1
)
Date of Conference: 1999
- Meeting Date :
- 13 Oct 1999-16 Oct 1999
- ISSN :
- 1094-687X
- Print ISBN:
- 0-7803-5674-8
- INSPEC Accession Number:
- 6441563
- Conference Location :
- Atlanta, GA
- Digital Object Identifier :
- 10.1109/IEMBS.1999.802067
- Product Type:
- Conference Publications
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