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In vivo infrared tomographic imaging of laser-heated blood vessels

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5 Author(s)
Telenkov, S.A. ; Biomed. Eng. Program, Texas Univ., Austin, TX, USA ; Tanenbaum, B.S. ; Goodman, D.M. ; Nelson, J.S.
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We demonstrate a method for infrared tomographic imaging of the initial three-dimensional (3-D) temperature increase of in vivo blood vessels following pulsed laser exposure. Using a time-sequence of infrared images recorded by a fast focal plane array camera as input data, a reconstruction algorithm is used to compute the initial 3-D temperature increases in the chick chorioallantoic membrane and port wine stain in human skin. The noncontact tomographic imaging method is relevant to various laser therapies that rely on a photothermal mechanism for selective modification of tissue and may find diagnostic application to determine optimal laser dosimetry, position, and size of targeted subsurface chromophores

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Selected Topics in Quantum Electronics, IEEE Journal of  (Volume:5 ,  Issue: 4 )