A practical 3D tomographic method for correcting patient head motion in clinical SPECT

Patient motion during brain SPECT studies can degrade resolution and introduce distortion. We have developed a correction method which incorporates a motion tracking system to monitor the position and orientation of the patient's head during acquisition. Correction is achieved by spatially repositioning projections according to the measured head movements and reconstructing these projections with a fully 3D algorithm. The method has been evaluated in SPECT studies of the Hoffman 3D brain phantom performed on a triple head camera with fan beam collimation. Movements were applied to the phantom and recorded by a head tracker during SPECT acquisition. Fully 3D reconstruction was performed using the motion data provided by the tracker. The correction accuracy was assessed by comparing the corrected and uncorrected studies with a motion-free study, both visually and by calculating the mean squared error (MSE). In all studies, motion correction reduced the distortion and improved the MSE by a factor of two or more. We conclude that this method can compensate for head motion under clinical SPECT imaging conditions