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FT-IR chemical imaging of biomineralized tissues using a mercury-cadmium-telluride focal-plane array detector

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5 Author(s)
Marcott, C. ; Miami Valley Labs., Procter & Gamble Co., Cincinnati, OH, USA ; Reeder, R.C. ; Paschalis, E.P. ; Boskey, A.L.
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A 64×64 mercury-cadmium-telluride (MCT) focal-plane array detector attached to an FT-IR microscope was used to spectroscopically image 5-μm slices of human bone tissue in the fingerprint region of the infrared spectrum. The protein, carbonate, and phosphate concentrations change as function of distance from an osteon. Changes in the phosphate IR band shapes also occur, suggesting a spatial dependence to the biomineralization process

Published in:

Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE  (Volume:2 )

Date of Conference:

30 Oct-2 Nov 1997