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Corrections for accidental coincidences and attenuation in maximum-likelihood image reconstruction for positron-emission tomography

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2 Author(s)
D. G. Politte ; Washington Univ., St. Louis, MO, USA ; D. L. Snyder

Reconstruction procedures that account for attenuation in forming maximum-likelihood estimates of activity distributions in positron-emission tomography are extended to include regularization constraints and accidental coincidences. A mathematical model is used for these effects. The corrections are incorporated into the iterations of an expectation-maximization algorithm for numerically producing the maximum-likelihood estimate of the distribution of radioactivity within a patient. The images reconstructed with this procedure are unbiased and exhibit lower variance than those reconstructed from precorrected data

Published in:

IEEE Transactions on Medical Imaging  (Volume:10 ,  Issue: 1 )