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We examine the performance of a cognitive radio system in a hostile environment where an intelligent adversary tries to disrupt communications by minimizing the system throughput. We investigate the optimal strategy for spoofing and jamming a cognitive radio network with a Gaussian noise signal over a Rayleigh fading channel. We analyze a cluster-based network of secondary users (SUs). The adversary may attack during the sensing interval to limit access for SUs by transmitting a spoofing signal. By jamming the network during the transmission interval, the adversary may reduce the rate of successful transmission. We present how the adversary can optimally allocate power across subcarriers during sensing and transmission intervals with knowledge of the system, using a simple optimization approach specific to this problem. We determine a worst-case optimal energy allocation for spoofing and jamming, which gives a lower bound to the overall information throughput of SUs under attack.