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RFID Tag Helix Antenna Sensors for Wireless Drug Dosage Monitoring

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8 Author(s)
Haiyu Huang ; Methodist Hosp. Res. Inst., Houston, TX, USA ; Peisen Zhao ; Pai-Yen Chen ; Yong Ren
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Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μ l/MHz for transdermal drug delivery monitoring and 2.76- μ l/MHz sensitivity for implanted drug delivery monitoring.

This paper presents the concept of using a specifically designed RFID tag helix antenna as the sensing agent to wirelessly monitor the drug dosage inside a capsule or reservoir. Such a convenient and low cost sensing mechanism can potentially be applied in transdermal or implanted controllable drug delivery. This paper presents the concept of using a specifically designed RFID tag helix antenna as the sensing agent to wirelessly monitor the drug dosage inside a capsule or reservoir. Such a convenient and low cost sensing mechanism can potentially be applied in transdermal or implanted controllable drug delivery.

Published in:

Translational Engineering in Health and Medicine, IEEE Journal of  (Volume:2 )