By Topic

Label-free plasmonic immunosensing for plasmodium in whole blood

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Sang-Yeon Cho ; Klipsch Sch. of Electr. & Comput. Eng., New Mexico State Univ., Las Cruces, NM, USA ; Briscoe, J.L. ; Hansen, I.A. ; Smith, J.K.
more authors

We present the first experimental demonstration of label-free malaria pathogen detection in whole blood lysate using plasmon nanostructures. Previous studies on plasmonic biosensing have measured antibody-antigen binding, proteinprotein interactions, and detection of bacteria. However, unlike our sensor, many of these works rely on complex optical setups to excite surface plasmon waves. The demonstrated plasmon sensor is a compact, highly sensitive, cost effective, selective diagnostic tool for many portable biosensing applications such as point-of-care diagnostics. To achieve malaria pathogen detection, we utilized a highly site-directed and stable antibody immobilization process on the nanostructure's surface. The measured refractive index sensitivity of the nanostructured sensor is 378 nm/RIU in the visible range.

Published in:


Date of Conference:

3-6 Nov. 2013