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We have developed the first patient-specific carbon nanotube (CNT) composite artificial tracheal implant tested on a porcine model in vivo. The experimental subject has survived with the implant with no apparent problems. Carbon nanocomposite material and the patient-specific approach have also been used to develop a voice prosthesis device as well as new microclips for wound closure. This article presents our experimental investigation with the carbon nanocomposite materials for constructing patient-specific ear, nose, and throat (ENT) implants.