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Real-time measurement of cardiac stroke volume using Compton backscattered X-rays

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4 Author(s)
M. D. Herr ; Pennsylvania State Univ., University Park, PA, USA ; J. J. McInerney ; R. L. Moore ; T. I. Musch

A technique which uses Compton backscattered X-rays to provide real-time measurements of stroke volume and cardiac output in the isolated working rat heart preparation is presented. A basic system was assembled and tested on mechanical models. Six isolated rat hearts were studied. Preliminary work shows that this X-ray backscatter detection system responds in a highly linear fashion and can detect rapid (>4 Hz) and small amplitude (<0.1 ml) changes in volume in the isolated and perfused rat heart. The amplitudes of the dynamic backscatter waveforms generally correlate well with directly measured stroke volumes and cardiac output

Published in:

Bioengineering Conference, 1990., Proceedings of the 1990 Sixteenth Annual Northeast

Date of Conference:

26-27 Mar 1990