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We present fiber-nonlinearity-tolerant transmission of polarization-division multiplexed binary phase-shift keying (PDM-BPSK) through a nonlinear noise squeezing (NLNS) effect that is achieved by optimized digital electronic dispersion precompensation. With the improved nonlinear tolerance, a 406.6-Gb/s superchannel consisting of eight 37.5-GHz-spaced 32-Gbaud Nyquist-filtered PDM-BPSK signals is transmitted over a 12800-km (160 × 80-km) EDFA-only amplified dispersion-unmanaged nonzero-dispersion-shifted fiber link. We establish a connection between the beneficial NLNS effect and the recently reported phase-conjugated twin wave (PCTW) concept and further generalize the PCTW concept to vector twin waves that are traveling through a fiber link along orthogonal dimensions such as time and space. Moreover, we apply the PCTW concept to wavelength-division-multiplexed (WDM) superchannel transmission by treating the entire WDM superchannel as a twin wave to further mitigate interchannel nonlinear effects. Through numerical simulations, we show that the generalized PCTW technique can effectively mitigate interchannel nonlinear impairments, in addition to mitigating intrachannel nonlinear impairments.