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The August 2013 special issue of the IEEE Transactions on Nuclear Science contains selected papers from the 2012 Radiation and Its Effects on Components and Systems (RADECS) Conference held September 24-28, 2012, in Biarritz, France. 92 papers presented at RADECS 2012 were submitted for consideration for this year's special issue. Those papers that appear in this special issue were able to successfully complete the review process before the deadline for the August issue. A few additional papers may appear in subsequent issues of the TRANSACTIONS.