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A new optical reference technique for biosensing applications is proposed. An association of a biosensor, based on a polymer planar cyclic microresonator vertically coupled to a straight waveguide, with a phase-sensitive optical low-coherence interferometer, based on two Michelson interferometers, is described. Such a technique gives information in the spatial and the spectral domains. The theory and the first measurements on biological molecules are presented. The results show that the proposed technique is relevant for biosensing since the concentration detection limit meets already the expected needs.