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Diffusion tensor imaging using a high-temperature superconducting resonator in a 3 T magnetic resonance imaging for a spontaneous rat brain tumor

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3 Author(s)
Lin, In-Tsang ; Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering, National Taiwan University, Taipei 106, Taiwan ; Yang, Hong-Chang ; Chen, Jyh-Horng

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This study investigates the peri-tumor signal abnormalities of a spontaneous brain tumor in a rat by using a 4 cm high-temperature superconducting (HTS) surface resonator. Fractional anisotropy (FA) values derived from diffusion tensor imaging reflect the interstitial characteristic of the peri-lesional tissues of brain tumors. Low FA indicates interstitial tumor infiltration and tissue injury, while high FA indicates better tissue integrity. Better delineation of tissue contents obtained by the HTS surface resonator at 77 K may facilitate therapeutic strategy and improve clinical outcomes.

Published in:

Applied Physics Letters  (Volume:102 ,  Issue: 6 )