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Breast cancer is an uncontrolled growth of breast cells. Cell in the body get divide, grow and die every day. This division and growth of cell is most of the in orderly manner but when their growth is out of control. The uncontrolled growth of cell forms the lump which is called as tumor. A tumor generally of two types benign (not dangerous) or malignant (dangerous to health). The malignant tumor which develops in breast is called as breast cancer. In this paper we use backpropagation neural network for classification of breast cancer with different neuron models. It can assist doctors for taking correct decisions.