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Ball-tipped fibers for laser angioplasty with the pulsed-dye laser

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6 Author(s)
Prince, M.R. ; Wellman Labs. of Photomed., Massachusetts Gen. Hospital, Boston, MA, USA ; LaMuraglia, G.M. ; Seidlitz, C.E. ; Prahl, S.A.
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A method of introducing high-intensity laser radiation into arteries has been developed and tested in amputated human limbs. The device consists of a small-diameter, flexible, quartz optical fiber which tapers to a large-diameter, smooth, rounded-ball tip. The small-ball tip minimizes the chance of mechanical dissection or perforation of the vessel wall. The spot size can be varied over a large range by varying the fiber input coupling, taper length, and numerical aperture. With 480-nm radiation, which is preferentially absorbed by atherosclerotic plaque and thrombus, at 80 μs pulse durations, the device effectively recanalized occluded human peripheral arteries creating a 2-3-mm diameter channel

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Quantum Electronics, IEEE Journal of  (Volume:26 ,  Issue: 12 )