By Topic

Scanning laser system for combined fluorescent diagnostics and photodynamic therapy: structural design, preliminary trials, and potentials

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)

Photodynamic therapy (PDT) is commonly performed by administration of porphyrin photosensitizers selectively retained by malignant tumors. Subsequent photoexcitation with UV-blue light causes fluorescence useful for diagnosis. Excitation by red light destroys the cancer tissue. The use of high-speed scanning of laser light as an alternative to conventional PDT which employs dispersed light to achieve uniformity of treatment is proposed. It is shown that treatment with scanned light beams produces photochemical effects in malignant animal tissue that are virtually the same as those caused by comparable treatments with diffused light. It is argued that undesirable thermal effects can be reduced by the use of focused, scanned laser beams in lieu of diffused light. It is also shown how concurrent analysis and treatment can proceed using a system of two laser beams

Published in:

Quantum Electronics, IEEE Journal of  (Volume:26 ,  Issue: 12 )