By Topic

Laser trapping in cell biology

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Wright, W.H. ; Dept. of Electr. & Comput. Eng., California Univ., Irvine, CA, USA ; Sonek, G.J. ; Tadir, Y. ; Berns, M.W.

Optical traps offer the promise of being used as noninvasive micromanipulators for biological objects. An analytical model was developed that accurately describes the forces exerted on dielectric microspheres while in a single-beam gradient force optical trap. The model can be extended to the trapping of biological objects. The model predicts the existence of a stable trapping point and effective trapping range. A minimum trapping power of ~5 mW and an effective trapping range of 2.4 μm were measured for 10-μm-diameter dielectric microspheres and are in reasonable agreement with expected results. In cell biology, the optical trap was used to alter the movement of chromosomes within mitotic cells in vitro and to hold motile sperm cells. Results for the mitotic cells indicate that chromosome movement was initiated in the direction opposite to that of the applied force

Published in:

Quantum Electronics, IEEE Journal of  (Volume:26 ,  Issue: 12 )