Referenced Items are not available for this document.
In dynamic positron emission tomography (PET) data analysis, regions of interest (ROIs) are analyzed by fitting a parametric model to the time-activity curve acquired after a radio-labeled tracer has been introduced into the patient's bloodstream. This procedure can be carried out for multiple ROIs and/or multiple injections of the same or a different radiopharmaceutical. The approach presented here takes advantage of prior knowledge that some of the parameters of those multiple fits are the same. Reduction of the total number of parameters to be estimated results in smaller statistical uncertainty for all parameter estimates, especially those common to multiple fits.
Published in:
Medical Imaging, IEEE Transactions on
(Volume:16
,
Issue:
5
)
Date of Publication: Oct. 1997
- Page(s):
- 675 - 683
- ISSN :
- 0278-0062
- INSPEC Accession Number:
- 5762771
- Digital Object Identifier :
- 10.1109/42.640758
- Product Type:
- Journals & Magazines
- Date of Current Version :
- 06 August 2002
- Issue Date :
- Oct. 1997
- Sponsored by :
- IEEE Engineering in Medicine and Biology Society
- PubMed ID :
- 9368123
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