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In this paper, an Artificial Immune System based on Hollandâs Classifier is proposed as a new method for network intrusion detection. This paper is not aimed to provide a comparative study but to give more understanding on the feasibility of combining Artificial Immune System and Hollandâs Classifier to detect network intrusion. This new Artificial Immune System, named AIS-CS, can attain higher than 90% intrusion detection with a false negative percentage below 10% and a fairly low false positive rate on a network composed of 50 regular nodes and 50 intruders. The experiments appear to suggest that the best performance can be found by setting the tolerization and the simulation parameters differently. Since there are numerous parameters involved, more experiments need to be performed to further measure this Holland classifier based Artificial Immune System.