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In this letter, we propose a novel power control scheme based on subcarrier exclusion in OFDMA macro/femto two-tier networks implemented by femto base station (FBS). The FBS derives its optimal transmission power and radius of neighboring area (NA) according to its own location and the macro mobile station (MMS) distribution to maximize its ergodic capacity under the constraints of maximum FBS transmission power and MMS performance requirement. Moreover, the macro neighboring area is derived, within which the FBS avoids its deployment. Our simulation verifies the applicability and efficiency of the proposed scheme.