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Recently, the death rate due to the liver cancer rises remarkably. To reduce the rate, the early detection of the disease is important. To detect diseases in early stage which are concern cancer, image diagnosis such as CT image is used in medical fields. On the other hand, the burden to a radiologist becomes increase. Therefore, the development of a system reducing the burden of the radiologist is important. In order to diagnose abnormalities based on medical imaging there are some reports. But, there is no report which is concern with detecting abnormality on liver disease based on temporal subtraction technique for abdominal CT image. As one of the methods to analyze abnormalities on visual screening, temporal subtraction technique is useful. This technique subtracts past image to current one. To obtain the good performance based temporal subtraction technique, image registration is most important task. In this paper, we propose a registration method for liver CT image using voxel matching techniques. We describe our registration method from two CT image which obtained deference time series and shows experimental results with discussion.