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With the unprecedented aging of population, chronic disease become a serious problem in modern medical area. Recent advances of wireless technology make the health monitoring in home to be more convenient for the chronic disease. Reducing the influence of the interference from the other wireless equipment is one of the most important problems in wireless physical parameter monitoring device in healthcare field, as reliable data transmitting is vital in medical care. In this paper, we propose a novel interference avoidance strategy that can greatly reduce the influence of the interference from other wireless equipment to wireless physical parameter monitoring devices in the hospital or home environment. Experimental results show that the strategy has good effect on interference avoidance and reduce the package loss rate.