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Social media is a mean to connect people through information sharing. It has been helping to use in various domains like education, business and human resource management. Healthcare domain however can be considered as one of the most potential domain to benefit from the social media participation in its different sub-domains like clinical observation, medications, professional training, patient education, home care and personalize care. However, there has always been a debate about contents' trust worthiness. Nevertheless, social media is totally discouraged to be considered in healthcare due to fear of open and unauthenticated contents. With all these reservations, the importance of information shared through social networks can never be ignored. This paper investigates the role of social media in patient centric healthcare. It highlights the special and active contribution of the social technologies in the domain of Decision Support System (DSS). The outcomes of this work will results in improved architecture for Smart CDSS system which is under development at UC Lab (Ubiquitous Computing Research Lab Kyung Hee University, South Korea).