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Purpose: To discuss the principles and procedures of building TCM conceptual system framework. Method: Using the experiences of the top-level structure in Western medicine to analyze the conceptual connotation of TCM basic theory, then to classify and determine the relations between ups and downs. Result: to form a conceptual system framework based on TCM basic theory with the characteristics of TCM. Conclusion: to construct a principle and procedure conforming to the standard and the feature of TCM basic theory is the key point in forming the framework.