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380V DC distribution is becoming a necessary choice for new telecom and datacenter power infrastructure. As state-of-the-art computing, routing and optical hub equipments continue to require more power, classic 48V distribution quickly becomes expensive to install and operate due to I2R losses; at the same time, AC distribution utilizing AC UPS becomes too expensive and complicated. While higher DC voltage can efficiently address the power system's total cost of ownership, system integrators need to interface existing 48V equipment in a simple and effective way. Similarly, equipment manufacturers need to design and make available new hardware that can directly accept the higher DC voltage. This paper presents power system architectures that address both needs, analyzing trade-offs at component as well as system partitioning level. Examples of end-to-end topologies are discussed in relation to newly released ETSI EN 300 132-3-1 standard compliance.