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A novel system for remote monitoring of metabolism in an animal model is proposed in this paper. The system is obtained by integrating bio-nano-sensors to detect single-metabolites, an electrochemical front-end made with off-the-shelf components, a radio frequency communication sub-system, and an antenna of new design. The system has been calibrated and tested for continuous monitoring of four different metabolites: glucose, lactate, glutamate, and adenosine triphosphate. Tests using animal models (mice) have been conducted to investigate tissue inflammation induced by the implanted bio-nano-sensors. These tests confirm that our system is suitable and reliable for remote monitoring of single-metabolites in experiments with animal models.
Published in:
Sensors Journal, IEEE
(Volume:13
,
Issue:
3
)
Date of Publication: March 2013
- Page(s):
- 1018 - 1024
- ISSN :
- 1530-437X
- INSPEC Accession Number:
- 13287770
- Digital Object Identifier :
- 10.1109/JSEN.2012.2231670
- Product Type:
- Journals & Magazines
- Date of Publication :
- 04 December 2012
- Date of Current Version :
- 29 January 2013
- Issue Date :
- March 2013
- Sponsored by :
- IEEE Sensors Council
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