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Co-clustering is a generalization of unsupervised clustering that has recently drawn renewed attention, driven by emerging data mining applications in diverse areas. Whereas clustering groups entire columns of a data matrix, co-clustering groups columns over select rows only, i.e., it simultaneously groups rows and columns. The concept generalizes to data “boxes” and higher-way tensors, for simultaneous grouping along multiple modes. Various co-clustering formulations have been proposed, but no workhorse analogous to K-means has emerged. This paper starts from K-means and shows how co-clustering can be formulated as a constrained multilinear decomposition with sparse latent factors. For three- and higher-way data, uniqueness of the multilinear decomposition implies that, unlike matrix co-clustering, it is possible to unravel a large number of possibly overlapping co-clusters. A basic multi-way co-clustering algorithm is proposed that exploits multilinearity using Lasso-type coordinate updates. Various line search schemes are then introduced to speed up convergence, and suitable modifications are proposed to deal with missing values. The imposition of latent sparsity pays a collateral dividend: it turns out that sequentially extracting one co-cluster at a time is almost optimal, hence the approach scales well for large datasets. The resulting algorithms are benchmarked against the state-of-art in pertinent simulations, and applied to measured data, including the ENRON e-mail corpus.