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We investigate the capability to perform K-edge imaging with the newly developed micro-CT PIXSCAN based on the XPAD3 hybrid pixel detector. The XPAD3 detector surface of 8 cm ×11 cm makes it possible to perform whole body mouse imaging. We present a proof of principle of K-edge imaging of mouse-size phantoms filled with Silver and Iodine solutions. Results are compared with standard X-ray absorption tomography for several solution densities.