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In-beam PET imaging for the control of heavy-ion tumour therapy

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8 Author(s)
Pawelke, J. ; Inst. fur Kern- und Hadronenphys., Forschungszentrum Rossendorf, Dresden, Germany ; Enghardt, W. ; Haberer, T. ; Hasch, B.G.
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A method for the in-situ control of the heavy-ion tumour therapy by means of positron emission tomography is introduced. This method is founded on the measurement of the dynamic spatial distributions of β+-emitters generated by nuclear fragmentation during the irradiation and their relation to the dose. In order to study this relationship and to derive the dose distribution from the measured β+-activity distribution, a framework of model calculations is used. Results of phantom experiments with 12C ion beams are presented, demonstrating good agreement between experiment and calculation as well as the possibilities and limits of the PET-technique for treatment plan verification and beam monitoring

Published in:

Nuclear Science, IEEE Transactions on  (Volume:44 ,  Issue: 4 )

Date of Publication:

Aug 1997

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