By Topic

Design of a high-resolution, high-sensitivity PET camera for human brains and small animals

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Moses, W.W. ; Lawrence Livermore Nat. Lab., CA, USA ; Virador, P.R.G. ; Derenzo, S.E. ; Huesman, R.H.
more authors

The authors present design parameters for a 3-D PET camera with high sensitivity (35 cm detector ring diameter, 15 cm axial field of view) and isotropic high resolution provided by detector modules capable of depth of interaction (DOI) measurement. Detector modules are made of LSO crystals (3 mm square by 30 mm deep)-the small module size and short decay time of LSO reduce the detector dead time by a factor of 14 compared to conventional EGO detector modules and narrow the coincidence window width to 4 ns. This yields an expected peak noise equivalent count rate of 800 kcps and noise equivalent sensitivity of 1370 kcps/μCi/cc with a 20 cm diameter phantom-three to five times higher than conventional scanners. With 5 mm fwhm DOI resolution, the expected reconstructed spatial resolution is <3.0 mm fwhm throughout the entire field of view. Depth of interaction measurement information is incorporated into the reconstruction algorithm by rebinning onto a regularly spaced grid. Attenuation correction is performed with an orbiting single transmission source

Published in:

Nuclear Science, IEEE Transactions on  (Volume:44 ,  Issue: 4 )